HIG1 hypoxia inducible domain family member 1B - definição. O que é HIG1 hypoxia inducible domain family member 1B. Significado, conceito
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O que (quem) é HIG1 hypoxia inducible domain family member 1B - definição


HIG1 hypoxia inducible domain family member 1B         
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
Hig1 hypoxia inducible domain family member 1b
HIG1 hypoxia inducible domain family member 1B is a protein that in humans is encoded by the HIGD1B gene.
Hypoxia-inducible factor         
  • Nobel Prize in Physiology or Medicine 2019: How Cells Sense and Adapt to Oxygen Availability. Under normoxic conditions, Hif-1 alpha is hydroxylated at two proline residues. It then associates with VHL and is tagged with ubiquitin resulting in proteasomal degradation. Under hypoxic conditions, Hif-1 alpha translocates to the cell nucleus and associates with Hif-1 beta. This complex then binds to the HRE region of the DNA resulting in the transcription of genes that are involved in a multitude of processes including erythropoesis, glycolysis, and angiogenesis.
FAMILY OF PROTEIN COMPLEXES
Hypoxia inducible factor; Hypoxia Inducible Factors; Hypoxia-inducible factor 1; Hypoxia inducible factor 1a; Hypoxia Inducible Factor; HIF-1; Hypoxia-inducible factors; Hypoxia inducible factors; Hypoxia signaling; Hypoxia-inducible factor-1; Hif1
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia.
Hilpda         
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
Hypoxia inducible lipid droplet-associated; HILPDA; C7orf68; HIG-2
Hypoxia inducible lipid droplet-associated (Hilpda, also known as C7orf68 and HIG-2) is a protein that in humans is encoded by the HILPDA gene.